Identification of new RNA modifying enzymes by iterative genome search using known modifying enzymes as probes

SnapShot: Histone-Modifying Enzymes

New Nomenclature for Chromatin-Modifying Enzymes

In the last ten years, the importance of chromatin modifications in many aspects of biology has become apparent. Several families of enzymes that modify histones have been identified, the majority of which are conserved throughout evolution. The enormous interest in this field has resulted in a very rapid rate of discovery of new enzymes, but this in turn has lead to a noncoherent nomenclature ...

Detection of Novel Flavonoid-Modifying Enzymes

Corresponding author: 9 Wolfgang R. Streit, Abteilung für Mikrobiologie und Biotechnologie, 10 Biozentrum Klein Flottbek, Universität Hamburg, 11 Ohnhorststraße 18, D-22609 Hamburg, Germany, 12 Telephone: (49) 428 16 463 13 Electronic mail: [email protected] 14 Copyright © 2013, American Society for Microbiology. All Rights Reserved. Appl. Environ. Microbiol. doi:10.1128/AEM.01077-...

Determination of lignin-modifying enzymes (LMEs) in Hyphodermella species using biochemical and molecular techniques

White-rot basidiomycetes are one of the most important lignolytic microorganisms. These fungi have been reported to secrete three main classes of lignin degrading enzymes: lignin peroxidases (LiPs), manganese peroxidases (MnPs) and laccases. In this study, for the first time the lignin degrading capability of two plant pathogens i.e. Hyphodermella rosae and H. corrugata was evaluated using both...

Chromatin-modifying enzymes in transcription and cancer

In recent years, our view of how gene expression is controlled has changed dramatically. The discovery of enzymes that modify histones has revealed that transcription is an enzymically driven process. Such modifications can recruit specific proteins and mediate chromatin changes that affect transcription either positively or negatively. Important biological pathways leading to cell proliferatio...